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Effect of a novel orally bioavailable CXCR4 inhibitor, AMD070, on the metastasis of oral cancer cells

Homma T, Fujii J

found that the lncRNA CRNDE triggers protective autophagy by upregulating ATG4B in HCC cells via sequestration of miR-543, whereas sorafenib therapy activates the CRNDE/ATG4B/autophagy pathway and reduces sorafenib sensitivity in HCC [86]

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