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Additionally, efficient capture and isolation of CTCs/clusters from cancer patient blood remains technically challenging

Jiang Y, Cheng J, Yang C, Hu Y, Li J, Han Y, et al

Here we review a dozen promising IN peptide therapeutics in preclinical and clinical development for neurodegenerative (Alzheimers, Parkinsons), neuropsychiatric (depression, PTSD, schizophrenia), and neurodevelopmental disorders (autism), with insulin, NAP (davunetide), IGF-1, PACAP, NPY, oxytocin, and GLP-1 agonists prominent among them

in fact, it can also favor cancer development due to its potential negative impact on anticancer immunity (366)

On examination, she had nonitchy, hyperpigmented macular lesions predominantly on the dorsum of the middle phalanges of the toes of both feet (Figure 1)