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CRISPR Screens The metabolism-focused human sgRNA library used was first described by Birsoy et al., 65 and screens were performed as described previously

On the contrary, the use of peptides/peptidomimetics has never been investigated in the FXS context, but it could represent a viable solution as it might result in a compensation of FMRP absence

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doi: 10.1111/imr.2018.281.issue-1 184 DixonSJLembergKMLamprechtMRSkoutaRZaitsevEMGleasonCEet al
