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Plateau Effect: The PFS curve for the Tech-Dara arm showed a distinct plateau after month 6, suggesting that for a significant portion of patients, this combination may offer a functional cure
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they only tested mitofusin-2 levels, an indicator for mitochondrial activity, which was unaltered 259
Remember that clinical trials failed to demonstrate statistically significant weight loss in the largest study, leading to development termination in 2007
