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To summarize, blocking antiporters can increase cell susceptibility to ferroptosis by decreasing the production of GSH [52]
Direct Interaction between Nrf2 and p21Cip1/WAF1 upregulates the Nrf2-mediated antioxidant response
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Moreover, significantly reduced expression of the mineralization marker, osteocalcin was observed, consistent with a failure of chondrocytes to initiate mineralization (Wang et al., 2006b)
