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Description
SchultzRWitteOWSchmeerC.Increased frataxin levels protect retinal ganglion cells after acute Ischemia/Reperfusion in the mouse retina in vivo
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Besides, it upregulates the synthesis of many other peptide hormones

Mice lacking the modifier subunit of GCL, have a 60% reduction in glutathione, accompanied by abnormal cortical gamma synchrony, decreased parvalbumin interneurons (PV-IN) and behavioral phenotypes relevant to schizophrenia.(49-51)
Active site residues U46, K48, Q81, and W136 are highlighted and shown as sticks
