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Additionally although signalling via growth factor receptors can be oncogenic the same receptors can also drive apoptosis within cancer cells ( IGF mutations do not occur frequently in cancer indicating that it is often not an initial driver of tumourigenesis (Simpson et al., 2017)

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In non-small cell lung cancer, a non-chromosomal structural maintenance protein complex subunit I G (NCAPG) regulates cell division

SF = substandard and falsified

( A ) Schematic of HIF-2 knockdown xenograft in vivo study