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While glutathione synthesis is controlled by multiple factors, GCL is the main determinant, because the rate-limiting step is the cellular level of the amino acid cysteine

Although milk yield did not exhibit a significant response to Met supplementation, there was a tendency for an increase of 0.28 kg/d and 0.31 kg/d in cows supplemented with HMTBa and Mepron, respectively (Zanton et al., 2014)

This may reflect specific compensatory metabolic rearrangement or changes in protein metabolism in the early stage of smoking or in the models, but results between animal and human cohorts are not always consistent (93)

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Taken together, although vitamin A, C, D, and E have been well described in respiratory diseases, including asthma, the role of the vitamins of the B group still needs to be investigated, together with the mysterious vitamin K, which can be a new player in the field of respiratory disorders