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Exposure of worms to low doses of H 2 O 2 (0.011 M) resulted in an increased sensory response of the ASH neurons which required the PRDX-2-mediated p38/PMK-1 signalling cascade [179]

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Although BPC-157 displays a high safety margin in animal models, controlled human studies are needed to confirm its efficacy and long-term tolerability. Sikiric, P