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Summarizing the data on the mechanisms of necroptosis, it can be noticed that this kind of programmed cell death requires mitochondrial and cytosolic ROS [216, 217]

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Hong T, Zhao T, He W, Xia J, Huang Q, Yang J, Gu W, Chen C, Zhang N, Liu Y, et al

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Recent research has demonstrated that the encoding of P4-135aa peptide by pseudogene MAPK6P4 is responsible for the phosphorylation of the S238 site in KLF15 which targets LDHA to increase its expression

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