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If results remain unexplained, particularly with very high levels, further investigation may include imaging or haematology referral depending on clinical context and associated abnormalities

For researchers using oral capsules, taking the compound 30 to 60 minutes before meals in a fasted state may enhance fat oxidation effects, though this recommendation is based on theoretical considerations rather than controlled studies

Morning with a meal is the simplest, most consistent approach

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Evidence-Based Alternatives for Healthy Weight Management For individuals seeking sustainable fat loss, NICE guidelines (CG189) recommend a comprehensive approach focusing on dietary modification, increased physical activity, and behavioural change rather than supplementation or injections