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You may need to adjust the needle to assure the tip of the needle is below the line of the solvent (liquid) into the powdered HCG

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When to increase dose Consider increasing if: Minimal response after 4-6 weeks at current dose No side effects at current dose Current dose below the higher end of recommended range Goals not being met with conservative approach Increase gradually, typically by 25-50% at a time

They may also raise the risk of bone loss, joint instability, and systemic side effects like elevated blood sugar or immune suppression

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