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Neuronal precursor survival Zn also plays a role in the survival of neuronal precursor cells, as it regulates the expression of both pro-survival pathways, like the ERK, Ak strain transforming (Akt), and nuclear factor (NF)-kB pathways, and pro-apoptotic cascades, such as the Jun N-terminal kinase (JNK) and p53 pathways
This model is valuable for targeted drugs screening to treat dormant LSCs in the microenvironment
2013 May 7;127(18):1888902
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[Abstract]2026 Mar:162:107589
