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[11] [12] How B12 Deficiency Affects the Nervous System Vitamin B12 plays essential roles in neurological health through several interconnected biochemical pathways

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Mild, transient fluid retention/edema and joint or muscle pain, each reported more often on MK-677 than placebo in the same trial, linked to elevated GH and IGF-1

Sikiric P, Seiwerth S, Deskovic S, et al

Loading Phase Initial period of higher-frequency dosing designed to build tissue concentrations quickly