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Analysis of pancreatic endocrine development in GDF11-deficient mice

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From each subject, a detailed brain image was first acquired, using a magnetization-prepared rapid gradient echo 47 high-resolution T1-weighted sequence (repetition time=6.6 ms, echo time=3.0 ms, flip angle=8, matrix=256240, slices =170, and slice thickness=1 mm)

Symptoms of deficiency can vary from person to person, but may include impaired brain function, tiredness and lack of energy, breathlessness and fatigue, headaches, pale skin, heart palpitations, loss of appetite and weight loss, anxiety and depression