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Kudaravalli P, John S, Sucralfate, in StatPearls , Treasure Island (FL): StatPearls Publishing, 2020

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Alterations in astrocytic activity is associated with many neurodegenerative and neuropsychiatric disorders including the development of chronic pain [231233]

In addition to platelet modulation, decreased levels of GSH increases local ROS in endothelial tissue contributing to a decrease in NO, an upregulation of NF- B, and subsequent increase in cytokine production and prothrombotic adhesion molecules