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Schulthei C, Willscher E, Paschold L, Gottschick C, Klee B, Henkes SS, et al

2 Clinical syndromes: clinical features, diagnosis and risk factors of BIPN 2.1 Clinical features Patients typically present with abnormal sensations in the extremities, with initial symptoms often manifesting in the feet

The volume of distribution (Vd) can be calculated by dividing the administered dose by the phenobarbital level

Fray et al., 1998
