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However, the clinical translation of such combination strategies still faces multiple challenges, including drug toxicity, cumulative side effects, dosage selection, and timing of administration

Using ChAT-GFP reporter mice allowed for tracking a massive expansion of CD4 + and CD8 + T cells at day 8 post-infection, followed by a rapid decline of Chat-GFP + splenic virus-specific T cells after LCMV clearance (31)

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Last reviewed: June 11, 2026 Last updated: June 11, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

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