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This explicit requirement for lipid peroxidation is a core feature of ferroptosis that distinguishes it from other forms of cell death: ferroptosis inhibitors cannot prevent other forms of cell death (Yang et al., 2014), and conversely classic inhibitors of necrosis, apoptosis, and autophagy do not modulate ferroptosis ( Figure 1 )

[Google Scholar] 66 **.Greenfield JM, Lucas S, Levine LA

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In this condition, the dehydrated, concentrated mucus layer retards MCC and compresses airway epithelial cells, promoting an inflammatory cascade that promotes cough, bronchoconstriction and chronic respiratory disease conditions