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Description
4.1 The function of MT in response to water stress Water stress causes an imbalance in the distribution of water in plants, disrupting cellular homeostasis and severely inhibiting plant growth

DrugBank 5.0: a major update to the DrugBank database for 2018
N.HambergM.SamuelssonB

Note that 2-PAM has an affinity for the acetylcholine anionic binding site on cholinesterase (right middle panel), which could explain the oxime related worsening of cholinergic side effects when 2-PAM is administered prior to the onset of action of atropine in the setting of organophosphate poisoning, by transiently preventing nerve-agent free cholinesterase from interacting with acetylcholine

13,14,15,16,17,18 Currently, the disease can only be diagnosed by DNA sequencing, and only a subset of individuals have detectable reductions in Asn levels in serum and cerebrospinal fluid, hindering the use of this test for initial screening
