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doi: 10.1002/alz.12008 225 LittleC
The formation of an intramolecular disulfide triggers the translocation of Yap1 into the nucleus, where it induces expression of antioxidant enzymes until reducing conditions are restored [108]
4 Oxidative stress Chronic low-grade inflammation can induce oxidative stress
[PubMed: 19153411] 758
Oxidative stress, a well-documented aspect of schizophrenia, is linked to both the pathogenesis of the disorder and the degeneration of neural circuits (38)
