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Hot-plate pain testing involves central COX mechanisms, whereas abdominal writhing measures peripheral COX enzyme effects, indicating that B12 may have both central and peripheral COX inhibiting properties (29)
Here are some tips for assessing vitamin B12 deficiency: Blood work - This is the most definitive way to check vitamin B12 levels
Chang and his team rotate between injection sites, such as the outer thigh, upper arm, or lower abdomen, to promote healing and ensure consistent absorption
Clin Endocrinol (Oxf)
