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doi: 10.1053/j.gastro.2008.10.080, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 54.Torres DM, Williams CD, Harrison SA

Retinoic acid-differentiated SH-SY5Y neuronal cells were exposed to acute (68 h) or chronic (9 days) iron loading to model transient versus prolonged age-related iron stress

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It may inhibit melanin production, leading to a more even skin tone and a reduction in hyperpigmentation

Chronic nicotine exposure induces oxidative stress, as evidenced by increased levels of mitochondrial-derived ROS in renal proximal tubular cells [179,180]