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Meanwhile, flavonoids like Oroxylin A stabilize the p53 protein, enhancing its suppression of glycolysisrelated genes [144]

, exosomes derived from MSCs increase the proliferation and migration of chondrocytes in vitro , and exert notable therapeutic effects in a collagenase-induced osteoarthritis mouse model [75], while exosome-laden hydrogels can drive cartilage regeneration in a rabbit model of cartilage defect [76]

Sf-9 cells were maintained at 28 C

doi: 10.3233/JAD-2010-1238

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