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however, continuous muscle injury triggers a chronic inflammatory response, which can aggravate the underlying lesions by degrading intact proteins, implying reduced performance and compromised health [52, 72, 73]

Testing cagrilintide efficacy in the DIO rat model Study design (rat DIO model): Key findings: In contrast to the mouse model, cagrilintide monotherapy reduced body weight by 9.5%0.7 at week 2 in the DIO rat model

Skin laxity is another concern with weight loss exceeding 15-20% of body weight

The H 2 O 2 content revealed a tendency similar to that of O 2 content