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Scientific literature describes L-carnitine as an essential cofactor in the carnitine shuttle system, which regulates the movement of fatty acyl groups across the mitochondrial membrane

Some authors recommend anatomopathological examination for diagnostic confirmation, although others sustain that the diagnosis is only clinical and follow-up is necessary to investigate changes in size, shape, and color of the lesion.2,4 Although the number of documented cases allows no definitive conclusions, a clinical diagnosis of congenital melanotic macule of the tongue should be considered in the presence of the following characteristics: single or multiple lingual melanotic lesions, presence of a macular lesion at birth with proportional growth, and absence of family history of systemic conditions associated with mucosal pigmentation.2 For acquired cases, lingual melanotic macules, although rare, should be considered in the differential diagnosis of pigmented lesions of the oral mucosa

Nutritional intake patterns shifted during the trial: the Med diet group increased their intake of olive oil, nuts and oily fish, and reduced consumption of carbohydrates and saturated fatty acids

Sometimes chemical solvents such as hexane may be used to extract oil from the copra

Effect of L-carnitine on lipid pattern in haemodialysis