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1 Introduction Solid tumors are made up of tumor cells and the tumor microenvironment (TME) that includes various cells (immune cells and mesenchymal cells) and extracellular matrix (ECM) (1, 2)

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[193] investigated the efficacy of SAMe in managing SZ symptoms in patients with the low-activity COMT polymorphism and found an improvement of aggressive behavior and quality of life following SAMe augmentation in SZ [193]

[6] Peng H, Wang J, Chen J, Peng Y, Wang X, Chen Y, Kaplan DL, Wang Q
