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The modern epidemic of syphilis

(2024) introduced an ultrasensitive electrochemical biosensor based on an ion-sensitive field-effect transistor (ISFET) for detecting cardiac troponin I (cTnI), a critical biomarker for acute myocardial infarction

The equivalent residue of thioredoxin reductase (H245) has been studied as a candidate active site base that deprotonates the structurally equivalent cysteine to C159 (C138) to promote reactivity of the thiol pair ( zero absorbance to demonstrate the portion of the traces missed due to the limitations of mixing for instrumentation used
doi: 10.1039/D3RA08936C

Within this group of 39 individuals, 9 had been randomised to placebo, 17 to Vitamin-B6 and 13 to Vitamin-B12