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We demonstrate the presence of an endometrial microbiota in the uterus of patients with endometriosis that is more diverse (greater Shannon Diversity Index (an estimator of species richness and evenness 49 ), and greater proportion of Other taxa) than that of symptomatic controls (patients with pelvic pain, but surgical absence of endometriosis)

Materials and methods Participant selection Regularly-menstruating (i.e., 2135 days in length) women who were medication-free, not medically ill (as assessed by history, physical exam, neurological exam, MRI, gynecological exam, pap smear within the last year, laboratory tests, and ECG), and not pregnant were recruited for the study

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Thus, the demonstrated leading role of the rapid heart disturbances and general vascular failure in the major vessels-induced occlusive syndromes [14,15,16,17,18,19,20], severe intoxication (i.e., alcohol, lithium) [21,22] and maintained intra-abdominal hypertension [23] suggest that an application of isoprenaline by its own can induce rapidly its own occlusion-like-syndrome, an early disturbance decisive for further isoprenaline-myocardial lesion progression

After imputation using knn (k = 7) 46 , the data was normalized using EigenMS 47,48 to account for sample-to-sample variability (Fig