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However, in contrast to TDMD pairing, which accommodates a 40 bend in the duplex, the fully paired duplex adopts a relatively straight conformation and thus exits AGO2 along a different trajectory (Fig

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Dwivedi, Exploration of natural compounds with anti-SARS-CoV-2 activity via inhibition of SARS-CoV-2 Mpro Available from:, Brief Bioinform

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doi: 10.1038/s41593-019-0532-y 294 SantosE
