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Another study using NR supplementation showed that doses up to 1000 mg per day for 10 weeks were well tolerated in patients affected by mild cognitive impairments (MCI) 246
Cytokine 29 (1), 3141
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In HK-2 cells, silencing Nrf2 expression abolished the protective effects of LicoA, confirming that Nrf2 activation is essential for mediating LicoAs reno protective actions
