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In the MISER trial reported by Bang et al., 26 of 32 surgical patients (81.3%) underwent cystogastrostomy, while three patients were converted to endoscopic management because of intraoperative cardiovascular instability or technical failure

In preclinical rodent research it is characterized as a cytoprotective and angiomodulatory agent, reported to influence the VEGFnitric-oxide signaling axis, modulate angiogenesis during muscle and tendon healing, and promote granulation-tissue and collagen formation at wound sites

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[PMC free article] [PubMed] [Google Scholar] 61.Sidossis LS, Stuart CA, Shulman GI, Lopaschuk GD, Wolfe RR

Gilbert (eds)