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Large pharmacovigilance reviews have found no clear increase in suicidality with semaglutide, and some cohort data hint at lower depression incidence, but causation is not established (McIntyre et al., 2024)

120Merlob P, Weber-Schndorfer C, Peters P, et al

This raises the possibility that GPX3 might protect interstitial fibrotic ECM from oxidative damage with a potential impact on the resolvability of fibrotic matrix

Oncogene 15 : 14611470 Hall AG

Key regulators of ferroptosis are also directly degraded by the lysosome
