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Ahmed, 2005

(PubMed) Ziegler D, Nowak H, Kempler P, Vargha P, Low PA

While acetaminophen itself does not produce cravings or compulsive drug-seeking behavior, its presence in opioid formulations contributes to prolonged misuse, increasing the likelihood of opioid addiction

Response: Sharpe, Goldsmith and Chalder fail to restore confidence in the PACE trial findings