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4.3 Effect on neuro-developmental Throughout the developmental process, the brain exhibits heightened energy demands for synthesizing fundamental cellular structures, neurotransmitters, nucleic acids, proteins, carbohydrates, and lipids that are indispensable for neuronal growth and myelination (46, 47)

doi: 10.1097/MED.0000000000000530 17 RikhiRShapiroMD
J Mol Biol 425: 292308, 2013

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma

Medication is one piece of the picture