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Description
Chronic and acute hyperinsulinemia initiates the hormone cascade that favors tissue growth by stimulating increased levels of free IGF1 and reducing levels of IGF binding protein3

Niki E (2016) Oxidative stress and antioxidants: distress or eustress

10.1007/s00204-016-1745-4 Arch

and immune signaling and inflammatory regulators (e.g., chemokines and cytokines)

doi: 10.1007/s00018-019-03253-8