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In OA, This iron overload is closely related to disease progression, as it not only directly induces chondrocyte apoptosis but also accelerates cartilage degradation by upregulating matrix-degrading enzyme expression (Jing et al., 2021a)

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[DOI] [PubMed] [Google Scholar] Tirouvanziam R, Conrad CK, Bottiglieri T, Herzenberg LA, Moss RB, Herzenberg LA

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