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Acknowledgments The authors would like to thank Namyang Dairy Products Co., Ltd for their support of this study and Editage (www.editage.co.kr) for the English language editing

Elhadi Yasir Ahmed Mohammed

We identified significant differences in the concentrations of gut-derived metabolites and leaky gut-related biomarkers between patients and controls

Discussion Although several guidelines do not recommend the use of antioxidants (including PTX) in the treatment of PD, several clinical trials, case reports, and review articles have been published on the use of antioxidants, including PTX alone or in combination with other antioxidant substances or other treatments [27,35,59,70,71,72,73,74,75,76,77,78,79,80,81,82,83,84,85,86,87,88,89,90,91,92,93,94,95,96,97,98,99,100]