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First, as a GSH-dependent peroxide reductase, GPX4 activity highly depends on cystine provided by System Xc /SLC7A11 to maintain GSH synthesis

Wu H, Zhou M, Xu J, Wang J, Tong J, Sun N, Qian M (2022) Determining a wide range of antibiotics and pesticides in poultry feathers using selective accelerated solvent extraction-liquid chromatography-mass spectrometry

Take a fluttering heartbeat, for example

Openings between defective endothelial cells explain tumor vessel leakiness

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