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Moreover, the control peptide F3, lacking Tyr 6 , Trp 7 and Leu 12, could not bind efficiently to glutathione Sepharose 4B beads (Table 3)

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240 The protein has also attracted interest in neurodegenerative conditions, e.g., owing to its elevated concentration in AD brains, accumulation in amyloid plaques and a range of other aggregates or inclusion bodies, and potentially neurotoxic contributions in complex with the A peptide
