methitrexate plus glutathione Methotrexate-induced hepatotoxicity-mechanism, clinical cases and treatment approaches | Toxicological Research Methotrexate and cardiovascular prevention: an

10.1002/biof.1533 12 BissacottiB

Using pharmacophore models and LigandScout, the researchers were able to identify potential pharmacological targets that might be used in the treatment of diabetes

Kaempferol increased ecto-ALP activity in rat brain endothelial cells, which was linked to increased insulin and MPP+ uptake [275,276], while sulforaphane upregulated glutathione S-transferases (GSTs) that participate in phase 2 drug metabolism at the BBB [127]

doi: 10.1021/bi201284u

Another cohort study adjusting for the established risk factors for PD and the intake of major fatty acids only revealed a negative association between the dietary monounsaturated fatty acids and the risk of PD in women, with no statistically significant association between the dietary saturated fatty acids, n-3 and n-6 fatty acids, and the risk of PD (109)