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That said, even with triple the vitamin B12 intake, pregnant mothers serum vitamin B12 dipped into the low-to-mid range of normal in this study

Protocol: Starting dose: 0.6mg daily for week 1 Escalation: Increase by 0.6mg weekly until reaching 3mg daily Timing: Same time daily, ideally before meals Cost: $1,300-1,500/month without insurance The established safety record spanning over 10 years provides reassurance for patients concerned about newer medications' long-term risks

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Scientific Reports 12:484

It is used in the treatment of nutritional megaloblastic anemias following gastrectomy and during pregnancy