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A number of activated transcription factors have been shown to be critical regulators of T cell metabolism, such as mTOR, AMPK and c-Myc (Fig

[DOI] [PubMed] [Google Scholar] 102.Crofts A.R

The upregulation of NADPH oxidases (NOX enzymes) in tumour cells and tumor-associated macrophages (TAMs) also contributes to oxidative stress [43]

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