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RR glycosides can inhibit the release of inflammatory cytokines and reduce inflammatory responses and oxidative stress damage through AMPK/NF-B/NLRP3 and other signal transduction pathways [9294]

However, the specific regulatory network of iron metabolism in PCOS has not yet been fully elucidated, and studies evaluating the potential benefits of reducing iron load, whether using animal models or PCOS populations, remain relatively scarce

doi: 10.1016/j.cell.2017.11.048 [DOI] [PubMed] [Google Scholar] 52

Cholinergic nervous system and glaucoma: from basic science to clinical applications

And it disrupts sleep, which compounds everything else
