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Most commercial Brazil nuts sold in grocery stores in the US are treated with propylene oxide (PPO), a fumigant used to kill pathogens and extend shelf life
In cell culture studies, -tocopherol was found to improve the formation of an adhesive junction (known as immune synapse) between nave T lymphocytes and antigen presenting cells (APC), which eventually prompted T cell activation and proliferation (see Disease Prevention) (6, 7)

However, the value of this evidence is reduced because of the use of gauze (a non-recommended treatment) in the control group

Science 327:16531657

(2024) 110:e3243
