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[DOI] [PubMed] [Google Scholar] 27.Kikuchi E, Margulis V, Karakiewicz PI, Roscigno M, Mikami S, Lotan Y, et al
60 In a subsequent trial, however, cetuximab in combination with concurrent, cisplatin-based chemoradiation failed to produce a survival benefit in head and neck cancer patients

The proposed mechanism of action is the inhibition of ceramide synthase by occupying sphingosine and fatty acyl-CoA interactions

doi: 10.1038/s41434-020-0141-0 [DOI] [PubMed] [Google Scholar] 220

Cells were collected, homogenized in 1x IF-0a solution by vortexing, adjusted to an optical density of 0.071 at 750 nm using a Genesys-5 spectrophotometer, and inoculated onto PM1 and PM2 plates
