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The Role of Glutamine in Gut Health and Digestion The impact of glutamine on gut health and digestion is as follows: Supporting the integrity of the gut lining : The cells that line the intestines, known as enterocytes, form a barrier that prevents harmful pathogens and toxins from entering the bloodstream

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Similarly, loss of the putative nutrient-sensing regulator GCN5-like 1 (GCN5L1) resulted in the simultaneous activation of transcription factor EB (TFEB)-mediated mitophagy and PGC-1-mediated mitobiogenesis, thereby increasing mitochondrial turnover [209]

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