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Retinal development is characterized by the differentiation of neural progenitor cells (NPCs) into various retinal cell types (Figure 1D), a process tightly regulated by DNA methylation, enabling the transition of the retina from embryonic to mature stages (Singh et al., 2017

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doi: 10.1016/j.jddst.2025.106862 229 Snchez-LpezE.EttchetoM.EgeaM

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However, when NADPH levels fall, the inhibition is relieved, the pathway is reactivated, and both NADPH and ribose 5-phosphate are synthesized

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