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LPS is a 1020 kDa protein located in the outer membrane of gram-negative bacteria, which is mainly transported across the epithelium via the transcellular route (58)

The effectiveness and purity of PCT drugs are concerns for many users (Grant et al., 2023b)

We highlight ongoing clinical trials evaluating the safety and efficacy of the most advanced senolytic approach, dasatinib and quercetin (D+Q), including an ongoing Phase II senolytic trial supported by the Alzheimers Drug Discovery Foundation (ADDF)