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In this regard, CD38 inhibitors may have beneficial effects upon conditions, where cellular calcium homeostasis is deregulated such as in hypertension, cardiac ischemia, asthma and dysfunctional labor [29, 21, 69, 72, 73]

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Protein-damaging stresses activate c-Jun N-terminal kinase via inhibition of its dephosphorylation: a novel pathway controlled by HSP72